The new Research Training Group 2413 “SynAGE” at the Otto von Guericke University, the Leibniz Institute for Neurobiology (LIN) and the German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany offers 13 PhD thesis projects for talented, skilled, and highly motivated students of the Life Sciences starting from January 1st, 2019.

All PhD positions are filled, we will keep you informed about open MD positions (start 10.2019).

TP1:
Dysbalanced protein homeostasis as a hallmark and intervention target for aging cells? (Daniela C. Dieterich)

TP2:
Autophagy mechanisms in the aging hippocampus (Oliver Stork)

TP3:
A nexus between DNA-hypomethylation and cognitive decline in healthy aging (Michael R. Kreutz)

TP4:
Molecular underpinnings of high-risk aging: Neuronal insulin signaling, amyloidosis and the metabolic syndrome (Michael R. Kreutz)

TP5:
The effect of immunosenescence on synapse composition in a chronic neuroinflammation model (Ildiko R. Dunay)

TP6:
Extracellular matrix-neuron-glia interactions during aging-associated cognitive decline and rejuvenation by ECM targeting (Alexander Dityatev)

TP7:
Targeting perisynaptic ECM mediated synaptic dysfunction in cerebral small vessel disease (Stefanie Schreiber & Alexander Dityatev)

TP8:
The perisynaptic extracellular matrix (ECM) of the aging brain: impact of enriched environment and neuromodulation on ECM composition and cognitive performance (Eckart D. Gundelfinger & Constanze I. Seidenbecher)

TP9:
Mechanosensitive and astrocytic contributions to synaptic plasticity during aging (Daniela C. Dieterich)

TP10:
Hippocampal interneuron circuits during cognitive decline (Oliver Stork)

TP11:
Impact of stress on aging of BDNF-dependent synaptic and cognitive functions (Volkmar Leßmann)

TP12:
Effects of L-DOPA on memory consolidation in high- and low-performing amyloid-negative older adults (Emrah Düzel)

TP13:
Learning from mistakes: Cholinergic modulation of interactions between performance monitoring and long-term memory (Markus Ullsperger)