Head of the Department of Functional Architecture of Memory at the Leibniz Institute for Neurobiology
Our research focuses on the medial temporal lobe (MTL) areas, which are damaged in aging and amnesia resulting in severe memory deficits. Our aim is to characterize the specific contribution of these areas to memory function. We essentially study the spatial and the temporal components of episodic memory as well as the selective contribution of each of these areas to encoding, retrieval, familiarity and recollection. We investigate memory function in healthy subjects, in aging, in animal models of amnesia and to a lesser extent in humans by combining innovative behavioral memory paradigms with state-of-the-art techniques such as molecular imaging, optogenetics, stereotactic lesions, 7T fMRI and mutagenesis.
Keywords: medial temporal lobe – memory – retrieval – aging – amnesia