Thomas Frodl

Head of the University Clinic for Psychiatry and Psychotherapy at the Otto von Guericke University Magdeburg

The central goal of our research is to identify underlying neurobiological processes and to find biomarkers for prediction of disease progression or for therapy response in psychiatric disorders. Research focus is in affective disorders, trauma, schizophrenia, dementia, ADHD and personality disorders. In 7 intradepartmental research groups we study: i) how stress or other environmental factors interact with genetic polymorphisms on structural and functional integrity of the brain as well as protein syntheses using multimodal imaging techniques, genetics, and proteomics, ii) neuroinflammation and related biomarkers in patients with schizophrenia and affective disorders, iii) inflammation as well as cellular and extracellular structures in post mortem brains of patients with schizophrenia and affective disorders, iv) neuroinflammation and early diagnosis in patients with dementia using CSF, blood markers and neuroimaging, v) clinical trials in patients with dementia, affective disorders, and schizophrenia, vi) epidemiology and risk for suicidality, vii) violence, aggression and forensic aspects.

Keywords: affective disorders – trauma – dementia – schizophrenia

Location: OVGU (FME)

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