Research Scientist at Molecular Physiology at the Leibniz Institute for Neurobiology Magdeburg
My previous study was focused at pharmacological and biophysical properties of neuronal nicotinic acetylcholine receptors (nAChRs) using electrophysiological tools. Investigating subunit composition of nAChRs and their single-channel properties is essential to understand their function in the brain as well as developing subunit specific drugs to treat neuropathological states. Our current research deals with the traffic and surface dynamics of synaptic calcium channels and their auxiliary subunits. With the use of electrophysiology we investigate how these auxiliary subunits interact with single calcium channel molecules, where they localize them and how they modulate neurotransmitter release in hippocampal synapses.
Keywords: ion channel – synaptic plasticity – single particle tracking – patch-clamp
Location: LIN
Webpage: Link